Synthesis and Characterization of Lipophilic Salts of Metformin to Improve Its Repurposing for Cancer Therapy

[Image: see text] Epidemiological evidence has accentuated the repurposing of metformin hydrochloride for cancer treatment. However, the extreme hydrophilicity and poor permeability of metformin hydrochloride are responsible for its poor anticancer activity in vitro and in vivo. Here, we report the...

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Detalles Bibliográficos
Autores principales: Saeed, Hiwa K., Sutar, Yogesh, Patel, Pratikkumar, Bhat, Roopal, Mallick, Sudipta, Hatada, Alyssa E., Koomoa, Dana-Lynn T., Lange, Ingo, Date, Abhijit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859945/
https://www.ncbi.nlm.nih.gov/pubmed/33553880
http://dx.doi.org/10.1021/acsomega.0c04779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859945/
https://www.ncbi.nlm.nih.gov/pubmed/33553880
http://dx.doi.org/10.1021/acsomega.0c04779

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