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VSP-17 suppresses the migration and invasion of triple-negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway

VSP-17, a novel peroxisome proliferator-activated receptor γ (PPARγ) agonist, has been previously demonstrated to suppress the metastasis of triple-negative breast cancer (TNBC) by upregulating the expression levels of E-cadherin, which is a key marker of epithelial-mesenchymal transition (EMT). How...

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Detalles Bibliográficos
Autores principales: Xu, Xiaotian, Liu, Meng, Yang, Yingying, Wei, Chengqiong, Zhang, Xiyang, Song, Hengzhi, Wang, Yuhui, Duan, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859999/
https://www.ncbi.nlm.nih.gov/pubmed/33650675
http://dx.doi.org/10.3892/or.2020.7916