Cargando…

VSP-17 suppresses the migration and invasion of triple-negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway

VSP-17, a novel peroxisome proliferator-activated receptor γ (PPARγ) agonist, has been previously demonstrated to suppress the metastasis of triple-negative breast cancer (TNBC) by upregulating the expression levels of E-cadherin, which is a key marker of epithelial-mesenchymal transition (EMT). How...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xiaotian, Liu, Meng, Yang, Yingying, Wei, Chengqiong, Zhang, Xiyang, Song, Hengzhi, Wang, Yuhui, Duan, Xiaoqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859999/ https://www.ncbi.nlm.nih.gov/pubmed/33650675 http://dx.doi.org/10.3892/or.2020.7916

Ejemplares similares

VSP-17, a New PPARγ Agonist, Suppresses the Metastasis of Triple-Negative Breast Cancer via Upregulating the Expression of E-Cadherin
por: Wang, Yuhui, et al.
Publicado: (2018)

GVS-12 attenuates non-alcoholic steatohepatitis by suppressing inflammatory responses via PPARγ/STAT3 signaling pathways
por: Wang, Yuhui, et al.
Publicado: (2019)

Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway
por: Xu, Xiaotian, et al.
Publicado: (2017)

Subchronic Oral Toxicity of Sodium p-Hydroxybenzoate in Sprague-Dawley Rats
por: Fan, Xiaoli, et al.
Publicado: (2022)

Developmental changes in abundance of the VSPβ protein following nuclear transformation of maize with the Soybean vspβ cDNA
por: Grando, Magali F, et al.
Publicado: (2005)

Diffusion Model for DAS-VSP Data Denoising
por: Zhu, Donglin, et al.
Publicado: (2023)

The Linker Pivot in Ci-VSP: The Key to Unlock Catalysis
por: Hobiger, Kirstin, et al.
Publicado: (2013)

Electro-chemical coupling in the voltage-dependent phosphatase Ci-VSP
por: Kohout, Susy C., et al.
Publicado: (2010)

Coupling between the voltage-sensing and phosphatase domains of Ci-VSP
por: Villalba-Galea, Carlos A., et al.
Publicado: (2009)

Structure-Function Investigation of Vsp Serotypes of the Spirochete Borrelia hermsii
por: Mehra, Rohit, et al.
Publicado: (2009)

Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP
por: Shen, Rong, et al.
Publicado: (2022)

The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution
por: Adam, Rodney D, et al.
Publicado: (2010)

Quantification of DAS VSP Quality: SNR vs. Log-Based Metrics
por: Titov, Aleksei, et al.
Publicado: (2022)

Cross Regulation of Sirtuin 1, AMPK, and PPARγ in Conjugated Linoleic Acid Treated Adipocytes
por: Jiang, Shan, et al.
Publicado: (2012)

Interleukin-17 promotes proliferation, migration, and invasion of trophoblasts via regulating PPAR-γ/RXR-α/Wnt signaling
por: Zhang, Zhuo, et al.
Publicado: (2022)

Jujuboside B Inhibits Neointimal Hyperplasia and Prevents Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration via Activation of AMPK/PPAR-γ Signaling
por: Ji, Zaixiong, et al.
Publicado: (2021)

CDDO, a PPAR-γ ligand, inhibits TPA-induced cell migration and invasion through a PPAR-γ-independent mechanism
por: Jang, Hye-Yeon, et al.
Publicado: (2022)

Crocin Improves Insulin Sensitivity and Ameliorates Adiposity by Regulating AMPK-CDK5-PPARγ Signaling
por: Fang, Kai, et al.
Publicado: (2020)

NUSAP1 promotes the metastasis of breast cancer cells via the AMPK/PPARγ signaling pathway
por: Qiu, Juanjuan, et al.
Publicado: (2021)

The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells
por: Ratzan, Wil, et al.
Publicado: (2019)

Voltage-sensing phosphatase (Vsp) regulates endocytosis-dependent nutrient absorption in chordate enterocytes
por: Ratanayotha, Adisorn, et al.
Publicado: (2022)

Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers
por: Loo, Ser Yue, et al.
Publicado: (2021)

Underexpression of peroxisome proliferator-activated receptor (PPAR)γ in PAX8/PPARγ-negative thyroid tumours
por: Marques, A R, et al.
Publicado: (2004)

Isolation, characterization and application of a lytic phage vB_VspM_VS1 against Vibrio splendidus biofilm
por: Duan, Xuemei, et al.
Publicado: (2023)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

Laquinimod Prevents Adipogenesis and Obesity by Down-Regulating PPAR-γ and C/EBPα through Activating AMPK
por: Wang, Guang, et al.
Publicado: (2020)

AMPK-PPARγ-Cidec Axis Drives the Fasting-Induced Lipid Droplet Aggregation in the Liver of Obese Mice
por: Li, Hongqiang, et al.
Publicado: (2022)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

AMPK-Dependent Metabolic Regulation by PPAR Agonists
por: Lee, Woo Hyung, et al.
Publicado: (2010)

Interaction between S4 and the phosphatase domain mediates electrochemical coupling in voltage-sensing phosphatase (VSP)
por: Mizutani, Natsuki, et al.
Publicado: (2022)

Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis
por: XiaoTian, Lei, et al.
Publicado: (2016)

Troglitazone Attenuates TGF-β1-Induced EMT in Alveolar Epithelial Cells via a PPARγ-Independent Mechanism
por: Zhou, Beiyun, et al.
Publicado: (2012)

Ampelopsin Improves Insulin Resistance by Activating PPARγ and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway
por: Zhou, Yong, et al.
Publicado: (2016)

Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway
por: Xu, Yingxi, et al.
Publicado: (2021)

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway
por: Wu, Liwei, et al.
Publicado: (2021)

Multiple and Diverse vsp and vlp Sequences in Borrelia miyamotoi, a Hard Tick-Borne Zoonotic Pathogen
por: Barbour, Alan G.
Publicado: (2016)

Abstract 51. Development of a Virtual Surgical Planning (VSP) Algorithm for Delayed Osseous Maxillomandibular Reconstruction
por: Stranix, John T., et al.
Publicado: (2017)

PPARγ and Apoptosis in Cancer
por: Elrod, Heath A., et al.
Publicado: (2008)

PPARγ, neuroinflammation, and disease
por: Mrak, Robert E, et al.
Publicado: (2004)

Nutraceuticals as Ligands of PPARγ
por: Penumetcha, Meera, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_1sbjdgku4koj614o7j9v2sknbo