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GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer
We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of smoothened (SMO). The three transcription factors...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860001/ https://www.ncbi.nlm.nih.gov/pubmed/33650666 http://dx.doi.org/10.3892/or.2021.7947 |