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Genome-wide DNA methylation profiling is able to identify prefibrotic PMF cases at risk for progression to myelofibrosis

BACKGROUND: Patients suffering from the BCR-ABL1-negative myeloproliferative disease prefibrotic primary myelofibrosis (pre-PMF) have a certain risk for progression to myelofibrosis. Accurate risk estimation for this fibrotic progression is of prognostic importance and clinically relevant. Commonly...

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Detalles Bibliográficos
Autores principales: Lehmann, Ulrich, Stark, Helge, Bartels, Stephan, Schlue, Jerome, Büsche, Guntram, Kreipe, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860011/
https://www.ncbi.nlm.nih.gov/pubmed/33541399
http://dx.doi.org/10.1186/s13148-021-01010-y