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microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and DKK1

BACKGROUND: Previous reports have identified that human bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) with their cargo microRNAs (miRNAs) are a promising therapeutic approach for the treatment of idiopathic pulmonary fibrosis (IPF). Therefore, we explored whether delive...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Lin, Yang, Kang, Xiuhua, Liu, Zhicheng, Zhang, Wei, Xu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860043/
https://www.ncbi.nlm.nih.gov/pubmed/33536061
http://dx.doi.org/10.1186/s13287-020-02083-x