3 (′)-5 (′) crosstalk contributes to transcriptional bursting

BACKGROUND: Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contrib...

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Detalles Bibliográficos
Autores principales: Cavallaro, Massimo, Walsh, Mark D., Jones, Matt, Teahan, James, Tiberi, Simone, Finkenstädt, Bärbel, Hebenstreit, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860045/
https://www.ncbi.nlm.nih.gov/pubmed/33541397
http://dx.doi.org/10.1186/s13059-020-02227-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860045/
https://www.ncbi.nlm.nih.gov/pubmed/33541397
http://dx.doi.org/10.1186/s13059-020-02227-5

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