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3 (′)-5 (′) crosstalk contributes to transcriptional bursting
BACKGROUND: Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contrib...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860045/ https://www.ncbi.nlm.nih.gov/pubmed/33541397 http://dx.doi.org/10.1186/s13059-020-02227-5 |