Cargando…

Multinuclear Nuclear Magnetic Resonance Spectroscopy Is Used to Determine Rapidly and Accurately the Individual pK(a) Values of 2-Deoxystreptamine, Neamine, Neomycin, Paromomycin, and Streptomycin

[Image: see text] Unambiguous assignments have been made for each individual pK(a) value of the amino group and guanidine substituents on 2-deoxystreptamine, neamine, neomycin, paromomycin, and streptomycin by pH-titration evaluation of their (1)H, (13)C, and (15)N (by (1)H-(15)N heteronuclear multi...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkhzem, Abdulaziz H., Woodman, Timothy J., Blagbrough, Ian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860104/
https://www.ncbi.nlm.nih.gov/pubmed/33553900
http://dx.doi.org/10.1021/acsomega.0c05138