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Multinuclear Nuclear Magnetic Resonance Spectroscopy Is Used to Determine Rapidly and Accurately the Individual pK(a) Values of 2-Deoxystreptamine, Neamine, Neomycin, Paromomycin, and Streptomycin
[Image: see text] Unambiguous assignments have been made for each individual pK(a) value of the amino group and guanidine substituents on 2-deoxystreptamine, neamine, neomycin, paromomycin, and streptomycin by pH-titration evaluation of their (1)H, (13)C, and (15)N (by (1)H-(15)N heteronuclear multi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860104/ https://www.ncbi.nlm.nih.gov/pubmed/33553900 http://dx.doi.org/10.1021/acsomega.0c05138 |