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Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling

Articular cartilage protects and lubricates joints for smooth motion and transmission of loads. Owing to its high water content, chondrocytes within the cartilage are exposed to high levels of hydrostatic pressure, which has been shown to promote chondrocyte identity through unknown mechanisms. Here...

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Detalles Bibliográficos
Autores principales: Maki, Koichiro, Nava, Michele M., Villeneuve, Clémentine, Chang, Minki, Furukawa, Katsuko S., Ushida, Takashi, Wickström, Sara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860130/
https://www.ncbi.nlm.nih.gov/pubmed/33310912
http://dx.doi.org/10.1242/jcs.247643