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Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling
Articular cartilage protects and lubricates joints for smooth motion and transmission of loads. Owing to its high water content, chondrocytes within the cartilage are exposed to high levels of hydrostatic pressure, which has been shown to promote chondrocyte identity through unknown mechanisms. Here...
Autores principales: | Maki, Koichiro, Nava, Michele M., Villeneuve, Clémentine, Chang, Minki, Furukawa, Katsuko S., Ushida, Takashi, Wickström, Sara A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860130/ https://www.ncbi.nlm.nih.gov/pubmed/33310912 http://dx.doi.org/10.1242/jcs.247643 |
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