Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha- versus beta-secretase activity, in vitro

The organic anion transporter Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1), also known as MRP1, has been demonstrated in murine models of Alzheimer's disease (AD) to export amyloid beta (Abeta) from the endothelial cells of the blood–brain barrier to the periphery, and t...

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Detalles Bibliográficos
Autores principales: Jepsen, Wayne M., De Both, Matthew, Siniard, Ashley L., Ramsey, Keri, Piras, Ignazio S., Naymik, Marcus, Henderson, Adrienne, Huentelman, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860133/
https://www.ncbi.nlm.nih.gov/pubmed/32878879
http://dx.doi.org/10.1242/bio.054627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860133/
https://www.ncbi.nlm.nih.gov/pubmed/32878879
http://dx.doi.org/10.1242/bio.054627

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