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Integrated transcriptome and proteome analyses identify novel regulatory network of nucleus pulposus cells in intervertebral disc degeneration

BACKGROUND: Degeneration of intervertebral disc is a major cause of lower back pain and neck pain. Studies have tried to unveil the regulatory network using either transcriptomic or proteomic analysis. However, neither have fully elucidated the exact mechanism of degeneration process. Since post-tra...

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Detalles Bibliográficos
Autores principales: Xu, Chen, Luo, Shengchang, Wei, Leixin, Wu, Huiqiao, Gu, Wei, Zhou, Wenchao, Sun, Baifeng, Hu, Bo, Zhou, Hongyu, Liu, Yang, Chen, Huajiang, Ye, Xiaojian, Yuan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860219/
https://www.ncbi.nlm.nih.gov/pubmed/33536009
http://dx.doi.org/10.1186/s12920-021-00889-z