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Inhibition of Lysozyme Amyloid Fibrillation by Silybin Diastereoisomers: The Effects of Stereochemistry

[Image: see text] Silybin is a flavonoid lignin compound consisting of two diastereomers with nearly equal molar ratios. It has been reported that silybin can effectively inhibit the aggregation of amyloid protein, but the difference between the two silybin diastereomers has been rarely studied. In...

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Detalles Bibliográficos
Autores principales: Chen, Xuanyu, Deng, Xiaomin, Han, Xingxing, Liang, Yinmei, Meng, Zhiping, Liu, Rui, Su, Wenqiang, Zhu, Huaxu, Fu, Tingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860231/
https://www.ncbi.nlm.nih.gov/pubmed/33553948
http://dx.doi.org/10.1021/acsomega.0c05788