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Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits

BACKGROUND: Identification of genetic risk factors that are shared between Alzheimer’s disease (AD) and other traits, i.e., pleiotropy, can help improve our understanding of the etiology of AD and potentially detect new therapeutic targets. Previous epidemiological correlations observed between card...

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Detalles Bibliográficos
Autores principales: Bone, William P., Siewert, Katherine M., Jha, Anupama, Klarin, Derek, Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Assimes, Themistocles L., Ritchie, Marylyn D., Voight, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860582/
https://www.ncbi.nlm.nih.gov/pubmed/33541420
http://dx.doi.org/10.1186/s13195-021-00773-z