Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion

Molecular docking studies were done to show the inhibitory effect of two naturally occurring biflavone based anti-HIV agents, hinokiflavone and robustaflavone against the SARS-CoV-2 spike (S) protein mediated attack on the human ACE2 receptors via membrane fusion mechanism. Nefamostat, a FDA approve...

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Detalles Bibliográficos
Autores principales: Mondal, Samiran, Karmakar, Abhijit, Mallick, Tamanna, Begum, Naznin Ara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860945/
https://www.ncbi.nlm.nih.gov/pubmed/33571798
http://dx.doi.org/10.1016/j.virol.2021.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860945/
https://www.ncbi.nlm.nih.gov/pubmed/33571798
http://dx.doi.org/10.1016/j.virol.2021.01.015

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