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Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion
Molecular docking studies were done to show the inhibitory effect of two naturally occurring biflavone based anti-HIV agents, hinokiflavone and robustaflavone against the SARS-CoV-2 spike (S) protein mediated attack on the human ACE2 receptors via membrane fusion mechanism. Nefamostat, a FDA approve...
Autores principales: | Mondal, Samiran, Karmakar, Abhijit, Mallick, Tamanna, Begum, Naznin Ara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860945/ https://www.ncbi.nlm.nih.gov/pubmed/33571798 http://dx.doi.org/10.1016/j.virol.2021.01.015 |
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