Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

Smallpox, caused by Variola virus (VARV), was eradicated in 1980; however, VARV bioterrorist threats still exist, necessitating readily available therapeutics. Current preparedness activities recognize the importance of oral antivirals and recommend therapeutics with different mechanisms of action....

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Detalles Bibliográficos
Autores principales: Hutson, Christina L., Kondas, Ashley V., Mauldin, Mathew R., Doty, Jeffrey B., Grossi, Irma M., Morgan, Clint N., Ostergaard, Sharon Dietz, Hughes, Christine M., Nakazawa, Yoshinori, Kling, Chantal, Martin, Brock E., Ellison, James A., Carroll, Darin D., Gallardo-Romero, Nadia F., Olson, Victoria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860987/
https://www.ncbi.nlm.nih.gov/pubmed/33536322
http://dx.doi.org/10.1128/mSphere.00927-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860987/
https://www.ncbi.nlm.nih.gov/pubmed/33536322
http://dx.doi.org/10.1128/mSphere.00927-20

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