Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays

[Image: see text] The precise determination of affinity and specificity is a crucial step in the development of new protein reagents for therapy and diagnostics. Paradoxically, the selection of protein binders, e.g., antibody fragments, from large combinatorial repertoires is a rapid process compare...

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Detalles Bibliográficos
Autores principales: Huovinen, Tuomas, Lindenburg, Laurens, Minter, Ralph, Hollfelder, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861142/
https://www.ncbi.nlm.nih.gov/pubmed/33397084
http://dx.doi.org/10.1021/acs.analchem.0c03992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861142/
https://www.ncbi.nlm.nih.gov/pubmed/33397084
http://dx.doi.org/10.1021/acs.analchem.0c03992

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