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Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays
[Image: see text] The precise determination of affinity and specificity is a crucial step in the development of new protein reagents for therapy and diagnostics. Paradoxically, the selection of protein binders, e.g., antibody fragments, from large combinatorial repertoires is a rapid process compare...
Autores principales: | Huovinen, Tuomas, Lindenburg, Laurens, Minter, Ralph, Hollfelder, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861142/ https://www.ncbi.nlm.nih.gov/pubmed/33397084 http://dx.doi.org/10.1021/acs.analchem.0c03992 |
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