N-Glycans and sulfated glycosaminoglycans contribute to the action of diverse Tc toxins on mammalian cells

Tc toxin is an exotoxin composed of three subunits named TcA, TcB and TcC. Structural analysis revealed that TcA can form homopentamer that mediates the cellular recognition and delivery processes, thus contributing to the host tropism of Tc toxin. N-glycans and heparan sulfates have been shown to a...

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Detalles Bibliográficos
Autores principales: Song, Nan, Chen, Lihong, Ren, Xingmei, Waterfield, Nicholas R., Yang, Jian, Yang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861375/
https://www.ncbi.nlm.nih.gov/pubmed/33539469
http://dx.doi.org/10.1371/journal.ppat.1009244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861375/
https://www.ncbi.nlm.nih.gov/pubmed/33539469
http://dx.doi.org/10.1371/journal.ppat.1009244

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