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Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency

Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane‐bound enzyme complex that is involved in both the tricarboxylic acid cycle and the electron transport chain, can lead to a variety of disorders. Recognized conditions with such mutatio...

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Detalles Bibliográficos
Autores principales: Al Khazal, Fatimah, Kang, Seungwoo, Nelson Holte, Molly, Choi, Doo‐Sup, Singh, Ravinder, Ortega‐Sáenz, Patricia, López‐Barneo, José, Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861419/
https://www.ncbi.nlm.nih.gov/pubmed/33247500
http://dx.doi.org/10.1096/fj.202002100R