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Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency
Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane‐bound enzyme complex that is involved in both the tricarboxylic acid cycle and the electron transport chain, can lead to a variety of disorders. Recognized conditions with such mutatio...
Autores principales: | Al Khazal, Fatimah, Kang, Seungwoo, Nelson Holte, Molly, Choi, Doo‐Sup, Singh, Ravinder, Ortega‐Sáenz, Patricia, López‐Barneo, José, Maher, L. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861419/ https://www.ncbi.nlm.nih.gov/pubmed/33247500 http://dx.doi.org/10.1096/fj.202002100R |
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