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The ubiquinone synthesis pathway is a promising drug target for Chagas disease

Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi). It was originally a Latin American endemic health problem, but now is expanding worldwide as a result of increasing migration. The currently available drugs for Chagas disease, benznidazole and nifurtimox...

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Detalles Bibliográficos
Autores principales: Nara, Takeshi, Nakagawa, Yukari, Tsuganezawa, Keiko, Yuki, Hitomi, Sekimata, Katsuhiko, Koyama, Hiroo, Ogawa, Naoko, Honma, Teruki, Shirouzu, Mikako, Fukami, Takehiro, Matsuo, Yuichi, Inaoka, Daniel Ken, Kita, Kiyoshi, Tanaka, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861437/
https://www.ncbi.nlm.nih.gov/pubmed/33539347
http://dx.doi.org/10.1371/journal.pone.0243855