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Canonical transient receptor potential 6 channel deficiency promotes smooth muscle cells dedifferentiation and increased proliferation after arterial injury

OBJECTIVE: Previous studies showed the benefit of canonical transient receptor potential 6 (TRPC6) channel deficiency in promoting endothelial healing of arterial injuries in hypercholesterolemic animals. Long-term studies utilizing a carotid wire-injury model were undertaken in wild-type (WT) and T...

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Detalles Bibliográficos
Autores principales: Smith, Andrew H., Putta, Priya, Driscoll, Erin C., Chaudhuri, Pinaki, Birnbaumer, Lutz, Rosenbaum, Michael A., Graham, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861475/
https://www.ncbi.nlm.nih.gov/pubmed/33554153
http://dx.doi.org/10.1016/j.jvssci.2020.07.002