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Beta-catenin activation and immunotherapy resistance in hepatocellular carcinoma: mechanisms and biomarkers
Mutations involving CTNNB1, the gene encoding beta-catenin, and other molecular alterations that affect the Wnt/beta-catenin signaling pathway are exceptionally common in hepatocellular carcinoma. Several of these alterations have also been associated with scarcity of immune cells in the tumor micro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861492/ https://www.ncbi.nlm.nih.gov/pubmed/33553649 http://dx.doi.org/10.20517/2394-5079.2020.124 |