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Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication

Hepatitis B virus (HBV) capsid or core protein (HBc) contains an N-terminal domain (NTD) and a C-terminal domain (CTD) connected by a short linker peptide. HBc plays a critical role in virtually every step of viral replication, which is further modulated by dynamic phosphorylation and dephosphorylat...

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Detalles Bibliográficos
Autores principales: Xi, Ji, Luckenbaugh, Laura, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861550/
https://www.ncbi.nlm.nih.gov/pubmed/33493210
http://dx.doi.org/10.1371/journal.ppat.1009230