Cargando…
Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model
Mitochondria are vital organelles inside the cell and contribute to intracellular calcium (Ca(2+)) dynamics directly and indirectly via calcium exchange, ATP generation, and production of reactive oxygen species (ROS). Arrhythmogenic Ca(2+) alternans in cardiac myocytes has been observed in experime...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861552/ https://www.ncbi.nlm.nih.gov/pubmed/33493168 http://dx.doi.org/10.1371/journal.pcbi.1008624 |