Prenylated quinolinecarboxylic acid compound-18 prevents sensory nerve fiber outgrowth through inhibition of the interleukin-31 pathway

Interleukin-31 (IL-31) is involved in excessive development of cutaneous sensory nerves in atopic dermatitis (AD), leading to severe pruritus. We previously reported that PQA-18, a prenylated quinolinecarboxylic acid (PQA) derivative, is an immunosuppressant with inhibition of p21-activated kinase 2...

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Detalles Bibliográficos
Autores principales: Ogura, Masato, Endo, Kumiko, Suzuki, Toshiyuki, Homma, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861556/
https://www.ncbi.nlm.nih.gov/pubmed/33539470
http://dx.doi.org/10.1371/journal.pone.0246630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861556/
https://www.ncbi.nlm.nih.gov/pubmed/33539470
http://dx.doi.org/10.1371/journal.pone.0246630

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