Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence

Cryptococcal disease is estimated to affect nearly a quarter of a million people annually. Environmental isolates of Cryptococcus deneoformans, which make up 15 to 30% of clinical infections in temperate climates such as Europe, vary in their pathogenicity, ranging from benign to hyper-virulent. Key...

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Detalles Bibliográficos
Autores principales: Roth, Cullen, Murray, Debra, Scott, Alexandria, Fu, Ci, Averette, Anna F., Sun, Sheng, Heitman, Joseph, Magwene, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861560/
https://www.ncbi.nlm.nih.gov/pubmed/33493169
http://dx.doi.org/10.1371/journal.pgen.1009313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861560/
https://www.ncbi.nlm.nih.gov/pubmed/33493169
http://dx.doi.org/10.1371/journal.pgen.1009313

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