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Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence
Cryptococcal disease is estimated to affect nearly a quarter of a million people annually. Environmental isolates of Cryptococcus deneoformans, which make up 15 to 30% of clinical infections in temperate climates such as Europe, vary in their pathogenicity, ranging from benign to hyper-virulent. Key...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861560/ https://www.ncbi.nlm.nih.gov/pubmed/33493169 http://dx.doi.org/10.1371/journal.pgen.1009313 |