Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions. In Drosophila ovaries, piRNA-loaded Piwi detects nascent transposon transcripts and instructs heterochromatin formation through the Panor...

Descripción completa

Detalles Bibliográficos
Autores principales: Eastwood, Evelyn L, Jara, Kayla A, Bornelöv, Susanne, Munafò, Marzia, Frantzis, Vasileios, Kneuss, Emma, Barbar, Elisar J, Czech, Benjamin, Hannon, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861614/
https://www.ncbi.nlm.nih.gov/pubmed/33538693
http://dx.doi.org/10.7554/eLife.65557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861614/
https://www.ncbi.nlm.nih.gov/pubmed/33538693
http://dx.doi.org/10.7554/eLife.65557

Ejemplares similares