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SuperGAG biopolymers for treatment of excessive bladder permeability

Few therapeutic options exist for treatment of IC/BPS. A novel high MW GAG biopolymer (“SuperGAG”) was synthesized by controlled oligomerization of CS, purified by TFF and characterized by SEC‐MALLS and 1H‐NMR spectroscopy. The modified GAG biopolymer was tested in an OVX female rat model in which b...

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Detalles Bibliográficos
Autores principales: Towner, Rheal A., Greenwood‐Van Meerveld, Beverley, Mohammadi, Ehsan, Saunders, Debra, Smith, Nataliya, Sant, Grannum R., Shain, Harrison C., Jozefiak, Thomas H., Hurst, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861891/
https://www.ncbi.nlm.nih.gov/pubmed/33540486
http://dx.doi.org/10.1002/prp2.709