Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways

OBJECTIVE: The aim of this study is to confirm the hepatocellular protective functions of apigenin and the molecular mechanism on liver fibrosis in mice. METHODS: Carbon tetrachloride (CCl(4)) and bile duct ligature (BDL) mouse fibrosis models were used to investigate the effects of apigenin on live...

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Detalles Bibliográficos
Autores principales: Ji, Jie, Yu, Qiang, Dai, Weiqi, Wu, Liwei, Feng, Jiao, Zheng, Yuanyuan, Li, Yan, Guo, Chuanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861947/
https://www.ncbi.nlm.nih.gov/pubmed/33574836
http://dx.doi.org/10.1155/2021/6651839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861947/
https://www.ncbi.nlm.nih.gov/pubmed/33574836
http://dx.doi.org/10.1155/2021/6651839

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