Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses

OBJECTIVE: To test the hypothesis that dimethyl fumarate (DMF, Tecfidera) elicits different biological changes from DMF combined with monoethyl fumarate (MEF) (Fumaderm, a psoriasis therapy), we investigated DMF and MEF in rodents and cynomolgus monkeys. Possible translatability of findings was expl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wipke, Brian T., Hoepner, Robert, Strassburger-Krogias, Katrin, Thomas, Ankur M., Gianni, Davide, Szak, Suzanne, Brennan, Melanie S., Pistor, Maximilian, Gold, Ralf, Chan, Andrew, Scannevin, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862084/
https://www.ncbi.nlm.nih.gov/pubmed/33468560
http://dx.doi.org/10.1212/NXI.0000000000000950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862084/
https://www.ncbi.nlm.nih.gov/pubmed/33468560
http://dx.doi.org/10.1212/NXI.0000000000000950

Ejemplares similares