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Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses

OBJECTIVE: To test the hypothesis that dimethyl fumarate (DMF, Tecfidera) elicits different biological changes from DMF combined with monoethyl fumarate (MEF) (Fumaderm, a psoriasis therapy), we investigated DMF and MEF in rodents and cynomolgus monkeys. Possible translatability of findings was expl...

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Detalles Bibliográficos
Autores principales:	Wipke, Brian T., Hoepner, Robert, Strassburger-Krogias, Katrin, Thomas, Ankur M., Gianni, Davide, Szak, Suzanne, Brennan, Melanie S., Pistor, Maximilian, Gold, Ralf, Chan, Andrew, Scannevin, Robert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862084/ https://www.ncbi.nlm.nih.gov/pubmed/33468560 http://dx.doi.org/10.1212/NXI.0000000000000950

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