DMPK mRNA Expression in Human Brain Tissue Throughout the Lifespan

OBJECTIVE: Myotonic dystrophy is a multisystem disorder caused by a trinucleotide repeat expansion on the myotonic dystrophy protein kinase (DMPK) gene. To determine whether wildtype DMPK expression patterns vary as a function of age, we analyzed DMPK expression in the brain from 99 donors ranging f...

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Detalles Bibliográficos
Autores principales: Langbehn, Kathleen E., Carlson-Stadler, Zoe, van der Plas, Ellen, Hefti, Marco M., Dawson, Jeffrey D., Moser, David J., Nopoulos, Peggy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862092/
https://www.ncbi.nlm.nih.gov/pubmed/33575482
http://dx.doi.org/10.1212/NXG.0000000000000537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862092/
https://www.ncbi.nlm.nih.gov/pubmed/33575482
http://dx.doi.org/10.1212/NXG.0000000000000537

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