Cargando…

Build-UPS and break-downs: metabolism impacts on proteostasis and aging

Perturbation of metabolism elicits cellular stress which profoundly modulates the cellular proteome and thus protein homeostasis (proteostasis). Consequently, changes in the cellular proteome due to metabolic shift require adaptive mechanisms by molecular protein quality control. The mechanisms vita...

Descripción completa

Detalles Bibliográficos
Autores principales: Ottens, Franziska, Franz, André, Hoppe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862225/
https://www.ncbi.nlm.nih.gov/pubmed/33398091
http://dx.doi.org/10.1038/s41418-020-00682-y