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The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

As the immune system develops with age, children combat infections better. HIV-1, however, targets an activated immune system, potentially rendering children increasingly permissive to HIV-1 infection as they grow. How HIV-1 fitness changes with age in children is unknown. Here, we estimated the wit...

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Detalles Bibliográficos
Autores principales: Nagaraja, Pradeep, Gopalan, Bindu P., D’Souza, Reena R., Sarkar, Debolina, Rajnala, Niharika, Dixit, Narendra M., Shet, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862260/
https://www.ncbi.nlm.nih.gov/pubmed/33542308
http://dx.doi.org/10.1038/s41598-021-82293-2