TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc

The central region of the intervertebral disc (IVD) is rich in proteoglycans, leading to a hyperosmotic environment, which fluctuates with daily loading. The cells of the nucleus pulposus (NP cells) have adapted to this environment via the function of tonicity enhancer binding protein (TonEBP), and...

Descripción completa

Detalles Bibliográficos
Autores principales: Snuggs, J. W., Tessier, S., Bunning, R. A. B., Shapiro, I. M., Risbud, M. V., Le Maitre, C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862284/
https://www.ncbi.nlm.nih.gov/pubmed/33542263
http://dx.doi.org/10.1038/s41598-021-81838-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862284/
https://www.ncbi.nlm.nih.gov/pubmed/33542263
http://dx.doi.org/10.1038/s41598-021-81838-9

Ejemplares similares