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SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation
In adult tissue, stem and progenitor cells must tightly regulate the balance between proliferation and differentiation to sustain homeostasis. How this exquisite balance is achieved is an area of active investigation. Here, we show that epidermal genes, including ~30% of induced differentiation gene...
Autores principales: | Li, Jingting, Xu, Xiaojun, Tiwari, Manisha, Chen, Yifang, Fuller, Mackenzie, Bansal, Varun, Tamayo, Pablo, Das, Soumita, Ghosh, Pradipta, Sen, George L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862286/ https://www.ncbi.nlm.nih.gov/pubmed/33542242 http://dx.doi.org/10.1038/s41467-021-21067-w |
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