Crystal structures of non-oxidative decarboxylases reveal a new mechanism of action with a catalytic dyad and structural twists

Hydroxybenzoic acids, like gallic acid and protocatechuic acid, are highly abundant natural compounds. In biotechnology, they serve as critical precursors for various molecules in heterologous production pathways, but a major bottleneck is these acids’ non-oxidative decarboxylation to hydroxybenzene...

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Detalles Bibliográficos
Autores principales: Zeug, Matthias, Markovic, Nebojsa, Iancu, Cristina V., Tripp, Joanna, Oreb, Mislav, Choe, Jun-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862292/
https://www.ncbi.nlm.nih.gov/pubmed/33542397
http://dx.doi.org/10.1038/s41598-021-82660-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862292/
https://www.ncbi.nlm.nih.gov/pubmed/33542397
http://dx.doi.org/10.1038/s41598-021-82660-z

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