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Crystal structures of non-oxidative decarboxylases reveal a new mechanism of action with a catalytic dyad and structural twists
Hydroxybenzoic acids, like gallic acid and protocatechuic acid, are highly abundant natural compounds. In biotechnology, they serve as critical precursors for various molecules in heterologous production pathways, but a major bottleneck is these acids’ non-oxidative decarboxylation to hydroxybenzene...
Autores principales: | Zeug, Matthias, Markovic, Nebojsa, Iancu, Cristina V., Tripp, Joanna, Oreb, Mislav, Choe, Jun-yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862292/ https://www.ncbi.nlm.nih.gov/pubmed/33542397 http://dx.doi.org/10.1038/s41598-021-82660-z |
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