Cytoplasmic vacuolation with endoplasmic reticulum stress directs sorafenib induced non-apoptotic cell death in hepatic stellate cells

The activated hepatic stellate cells (HSCs) are the major cells that secrete the ECM proteins and drive the pathogenesis of fibrosis in chronic liver disease. Targeting of HSCs by modulating their activation and proliferation has emerged as a promising approach in the development of anti-fibrotic th...

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Detalles Bibliográficos
Autores principales: Sharma, Sachin, Ghufran, Shaikh Maryam, Ghose, Sampa, Biswas, Subhrajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862314/
https://www.ncbi.nlm.nih.gov/pubmed/33542321
http://dx.doi.org/10.1038/s41598-021-82381-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862314/
https://www.ncbi.nlm.nih.gov/pubmed/33542321
http://dx.doi.org/10.1038/s41598-021-82381-3

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