Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes

Presenilin 1 (PS1) and Presenilin 2 (PS2) are predominantly known as the catalytic subunits of the γ-secretase complex that generates the amyloid-β (Aβ) peptide, the major constituent of the senile plaques found in the brain of Alzheimer's disease (AD) patients. Apart from their role in γ-secre...

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Detalles Bibliográficos
Autores principales: Contino, Sabrina, Suelves, Nuria, Vrancx, Céline, Vadukul, Devkee M., Payen, Valery L., Stanga, Serena, Bertrand, Luc, Kienlen-Campard, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862347/
https://www.ncbi.nlm.nih.gov/pubmed/33551720
http://dx.doi.org/10.3389/fnins.2020.586108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862347/
https://www.ncbi.nlm.nih.gov/pubmed/33551720
http://dx.doi.org/10.3389/fnins.2020.586108

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