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Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes

Presenilin 1 (PS1) and Presenilin 2 (PS2) are predominantly known as the catalytic subunits of the γ-secretase complex that generates the amyloid-β (Aβ) peptide, the major constituent of the senile plaques found in the brain of Alzheimer's disease (AD) patients. Apart from their role in γ-secre...

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Detalles Bibliográficos
Autores principales:	Contino, Sabrina, Suelves, Nuria, Vrancx, Céline, Vadukul, Devkee M., Payen, Valery L., Stanga, Serena, Bertrand, Luc, Kienlen-Campard, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862347/ https://www.ncbi.nlm.nih.gov/pubmed/33551720 http://dx.doi.org/10.3389/fnins.2020.586108

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