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Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle

Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin structural transitions, but how remains unclear. To explore...

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Detalles Bibliográficos
Autores principales: Halsall, John A., Andrews, Simon, Krueger, Felix, Rutledge, Charlotte E., Ficz, Gabriella, Reik, Wolf, Turner, Bryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862352/
https://www.ncbi.nlm.nih.gov/pubmed/33542322
http://dx.doi.org/10.1038/s41598-021-82539-z