Cargando…
Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin structural transitions, but how remains unclear. To explore...
Autores principales: | Halsall, John A., Andrews, Simon, Krueger, Felix, Rutledge, Charlotte E., Ficz, Gabriella, Reik, Wolf, Turner, Bryan M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862352/ https://www.ncbi.nlm.nih.gov/pubmed/33542322 http://dx.doi.org/10.1038/s41598-021-82539-z |
Ejemplares similares
-
Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines
por: Terrenoire, Edith, et al.
Publicado: (2015) -
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
por: Hahn, Oliver, et al.
Publicado: (2017) -
Global Mapping of DNA Methylation in Mouse Promoters Reveals Epigenetic Reprogramming of Pluripotency Genes
por: Farthing, Cassandra R., et al.
Publicado: (2008) -
Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response
por: Halsall, John A, et al.
Publicado: (2015) -
Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success
por: Halsall, John A., et al.
Publicado: (2016)