Solubility assessment of single-chain antibody fragment against epithelial cell adhesion molecule extracellular domain in four Escherichia coli strains

BACKGROUND: Overexpression of the EpCAM (epithelial cell adhesion molecule) in malignancies makes it an attractive target for passive immunotherapy in a wide range of carcinomas. In comparison with full-length antibodies, due to the small size, the scFvs (single-chain variable fragments) are more su...

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Detalles Bibliográficos
Autores principales: Javadian, Fatemeh Sadat, Basafa, Majid, Behravan, Aidin, Hashemi, Atieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862456/
https://www.ncbi.nlm.nih.gov/pubmed/33543415
http://dx.doi.org/10.1186/s43141-021-00126-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862456/
https://www.ncbi.nlm.nih.gov/pubmed/33543415
http://dx.doi.org/10.1186/s43141-021-00126-1

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